What Bacteria is Ashwagandha Effective Against?

Ashwagandha can fight different types of common bacteria that cause disease.

Growing evidence indicates that many bacteria that cause infections in humans have developed resistance to multiple antibiotics, making new herbal antimicrobial agents even more important. In recent lab experiments, whole-plant extracts of ashwagandha were shown to be effective against a number of gram negative and gram positive bacteria that can cause serious illness:8

Evidence of Ashwagandha’s Antibacterial Activity

In lab experiments separate water extracts of ashwagandha alkaloids and a mix of essential oils and phenolic compounds (flavanoids) from ashwagandha demonstrated strong inhibition of MRSA. Flavanoids are known antioxidant compounds in plants. The added antioxidant activity of the phenolic extract helped reduce inflammation associated with infection as well.27

Ashwagandha was found to be particularly potent against E. coli and P. aeruginosa. This is particularly important since both of these bacteria have shown increasing resistance to antibiotics worldwide. P. aeruginosa has a reputation of being difficult to treat because it is naturally resistant to many antibiotics. Recent cases have been reported of P. aeruginosa resistance to the few antibiotics that have been effective (e.g., fluoroquinolones and aminoglycosides). Over the past 10 years E. coli has become increasingly resistant to both common and more potent antibiotic (e.g., fluoroquinolones).8, 28

Leishmania infects hundreds of thousands of people around the world every year, with the highest incidence in tropical regions where sandflies are common. A potentially deadly disease, the parasitic species that cause it are becoming resistant to standard drug treatments, leading to research into traditional Ayurvedic treatments. Recent lab studies have demonstrated that the withaferin A compound from ashwagandha extracts consistently inhibit the Leishmania donovani version of the parasite. L. donovani is primarily responsible for visceral leishmaniasis, with a 75-100% 2-year mortality rate for untreated cases, especially in people with weakened immune systems.32, 33

Ashwagandha may be able to reduce susceptibility to whooping cough. Results of an animal study demonstrated that mice given a diet supplemented with ashwagandha root extracts had lower rates of infection than the untreated control group. It is unclear whether this benefit is due to ashwagandha’s antibacterial or immune-boosting qualities, or possibly even both.30

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Stomach and intestinal infection with symptoms such as
diarrhea and vomiting.
With many more unreported.
Unvaccinated infants under a year old are at
the highest risk.